Subconjunctival Injection of Polymyxin B

Treatment of corneal infection with ps. pyocyanea by subconjunctival injection of polymyxin E.

THE properties of polymyxin in relation to ocular therapeutics have recently been discussed at some length ; the penetration of this antibiotic into the eye of the rabbit after subconjunctival injection was estimated and the results obtained in the treatment of corneal infection experimentally produced with Ps. pyocyanea have been reported (Ainslie and Smith, 1951). It is well known that this t...

Administering a subconjunctival injection

• Position the patient lying comfortably with his/her head supported on a pillow. • Reassure the patient that adequate anaesthetic drops will be instilled before the injection is given. • Instill anaesthetic drops at five-minute intervals over half an hour – a minimum of six drops. • Away from the patient’s view, draw up the prescribed medication using the 21G needle (Figure 1). • Change to the...

Systemic absorption of Soframycin after subconjunctival injection.

Subconjunctival bevacizumab injection in treatment of pterygium.

This study determined the clinical effect of subconjunctival administration of bevacizumab in patients with primary and recurrent pterygium. The study was an off-label, single-dosing, interventional case series involving 22 patients with primary and recurrent pterygium. They received subconjunctival bevacizumab (0.2 cc). Pterygium vascularity and thickness was graded. The size of the pterygium ...

Polymyxin b: controlled biosynthesis.

The polymyxins form a group of closely related strongly basic cyclicpeptide antibiotics with a rather specific activity against gram-negative bacteria. The most well-known and commercially produced members are poly-myxin B and E (colistin). These two consists of polymyxin B1, B2, B3 and E1, E2, E " the single components of them differing only in the fatty acid moiety of the side chain attached ...